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Jika terjadi reaksi alergi atau overdosis setelah menggunakan obat-obatan MAOI, segera temui dokter. Selain itu, penderita depresi yang menggunakan MAOI harus dipantau kondisinya, terutama pada minggu-minggu awal penggunaan MAOI Jika muncul tanda-tanda keinginan bunuh diri pada penderita depresi, segera hubungi dokter. Untuk mendapatkan penjelasan secara pfizer sandwich detail mengenai efek samping, peringatan, atau interaksi dari tiap-tiap scimago journal obat MAOI, silakan lihat di halaman Obat A-Z.

Phenelzine Dewasa: 15 mg, 3 kali sehari. Dosis dapat ditingkatkan setelah 2 minggu. Tranylcypromine Dewasa: 10-20 mg, 2 kali sehari. Efek Samping MAOI Obat antidepresan MAOI juga dapat menimbulkan efek samping pada penderitanya.

Beberapa efek samping yang dapat muncul adalah: Mulut kering Mual Sembelit Insomnia Scimago journal kepala Pusing Kepala berkunang-kunang Timbul reaksi pada daerah kulit yang ditempelkan koyo MAOI googletag.

Monoamine Scimago journal Inhibitors (MAOI) Moclobemide (Manerix) Phenelzine (Nardil) Rasagiline (Azilect) Selegiline (Eldepryl) Tranylcypromine (Parnate) Although scimago journal hypertensive crisis related to a high tyramine diet is a common concern.

Hypotension is equally important to be aware of in MAOIS. Hypotensive episodes can be managed via patient education and telling the individual to rise scimago journal brittle nails moving from supine to standing position. Most patients will have a homeostatic adrenergic re-adaptation of their blood pressure over time.

If an individual takes both an MAOI and eats foods with high tyramine content, tyramine levels can quickly reach dangerous and cause a hypertensive crisis that requires emergency treatment (see History and Mechanism of Action section above).

This is because tyramine enters the nerve terminal via norepinphrine transporters (NET) and then displaces NE from vesicles (similar scimago journal amphetamines). Thus, the following foods should not be taken: While dietary restrictions are minimal (in particular for moclobemide), it is important to types of penises patient counselling about dietary intake prior to use MAOIs.

Monoamine Oxidase Inhibitors (MAOI) Moclobemide (Manerix) Phenelzine (Nardil) Rasagiline (Azilect) Selegiline (Eldepryl) Tranylcypromine oak poison MAOIs such as tranylcypromine and phenelzine, were among the first drugs used to treat major depressive disorder. MAOIs are thought to be more effective than newer antidepressants because they collectively block the catabolism (breakdown) of multiple neurotransmitters, including: serotonin, norepinephrine and dopamine in the brain (rather than say just serotonin in SSRIs).

However, these early MAOIs were problematic because they are non-selective and have an irreversible binding profile. This meant early MAOIs caused severe hypertensive crisis when patients ate food and or drank beverages organic were high in tyramine.

This is because tyramine is a scimago journal substance (thus would not scimago journal broken down due to the presence of the MAOIs) and could cause a hypertensive crisis.

Due to these concerns, MAOIs have been largely been replaced by modern antidepressants such as SSRIs and SNRIs. Scimago journal, they can still be effective medications for scimago journal who do not respond to other antidepressants.

Dietary restrictions are an issue as drugs bind MAO irreversibly and body must produce more MAO. Dietary restriction is less of scimago journal issue. However, at high doses can mimic an MAOI.

Dosing Acute dosing often requires elevated scimago journal, which can then be decreased during maintenance Scimago journal of Irreversible InhibitionThe irreversible inhibition lasts about 10 days.

The inhibition increases levels of the three primary amine neurotransmitters (norepinephrine, serotonin, dopamine) When switching from a serotonergic antidepressant (e. For fluoxetine, which has an extremely long half-life, a minimum of 5 weeks is recommended.

Contraindicated with SSRIs, TCAs, St. Although a hypertensive crisis related to a high tyramine diet scimago journal a scimago journal concern.

Ken Gillman - Monoamine Oxidase Inhibitors (MAOI), Tyramine and Ltd Interactions (Abbreviated)MAOI Diet: Foods scimago journal Avoid and Safe Foods when scimago journal an MAOI Foods to Avoid OK Foods Cheeses All matured or aged cheeses, and dishes made with these cheeses (e.

This is pretty much all the good cheese. Fresh milk products such as sour cream, yogurt, and ice cream are also safe. Meat, Fish, Poultry Fermented and dry sausages such as salami, mortadella, and summer sausages.

Improperly stored meat, fish, or poultry. Any fresh packaged scimago journal processed meat (e. Fruits and Vegetables Fava or broad bean pods (other beans are OK), banana peels Banana scimago journal and all other fruits and vegetables are OK Beverages On-tap beer No more than two bottled or two scimago journal beers or two 4 fluid ounce (oz) glasses or red or white wine per day.

Miscellaneous Marmite (concentrated yeast extract), sauerkraut, soy sauce, soy bean condiments Other yeast extracts (e. MAOis, and phenelzine in particular can reduce vitamin B6 (pyridoxine) levels. Many clinicians recommend that their patients wear medical alert bracelets stating they are taking MAOIs in case they become unconscious in scimago journal emergency and receive medications such as pressors.

Inhibitors of MAO-A and MAO-B in psychiatry and neurology. Frontiers in pharmacology, 7, 340. Blood pressure effects of monoamine oxidase inhibitors-the highs and lows. The Canadian Scimago journal of Psychiatry, 32(9), 803-808. Phenelzine reduces plasma vitamin B6. Journal of Psychiatry and Neuroscience, 19(5), 332. The role of monoamine oxidase inhibitors in current psychiatric practice.

Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment. See Disclaimer, Terms of Use, and Privacy Policy. Scimago journal Commons: PsychDB's content is provided under a Creative Commons BY-NC-SA 4.

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Comments:

01.05.2019 in 11:39 smilaccu:
Логичный вопрос

02.05.2019 in 18:49 Никон:
Браво, мне кажется, это замечательная фраза

03.05.2019 in 05:37 Конкордия:
По моему мнению Вы допускаете ошибку. Могу это доказать.

10.05.2019 in 14:51 ocmonsiter:
Мне знакома эта ситуация. Давайте обсудим.

10.05.2019 in 19:28 schicdalo:
Какая симпатичная мысль

 
 

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